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A POWERFUL NEW GENERATION OF DIAGNOSTIC TOOLS The HistoSondas® are new single stranded DNA probes for chromogenic visualization of gene expression by in situ hybridization.
The characteristics of these innovative new probes set them apart from those already on the market.
The HistoSondas® consist of single stranded DNA fragments whose lengths are between 10 and 30 times greater than commercial oligo probes (the length of a HistoSonda® is between 200 and 1300 nucleotides). In the probe DNA thymines are substituted for deoxyuridines labeled with digoxigenin.
The probe DNA is targeted against RNA expressed by genes of interest and therefore the HistoSondas® are probes for the detection of gene expression. The HistoSondas® are specifically designed to be used on formalin-fixed and paraffin embedded tissue sections. HistoSonda® Technical Manual HistoSonda® Brochure |
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