RNAzol®RT is the most effective reagent for isolation of total RNA and small RNA from samples of human, animal, plant, bacterial and viral origin. This patent-pending reagent (1) provides higher yield and quality of isolated RNA than previous reagents based on the single-step method. RNAzol®RT isolates pure and undegraded RNA that is ready for RT-PCR without DNase treatment.

RNAzol®RT separates RNA from other molecules in a single-step based on the interaction of phenol and guanidine with cellular components. No chloroform-induced phase separation is necessary to obtain pure RNA. Supplementing RNAzol®RT with water makes DNA, proteins and polysaccharides insoluble.