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Kapa Biosystems

Despite the various claims of other reagents suppliers, all commercially available Taq polymerase is the same wild-type enzyme-any differences in performance are due to buffer formulation and/or enzyme concentration.
 
There are only a limited number of DNA polymerases that have been modified to improve their performance for laboratory applications. Kapa Biosystems' next-gen PCR reagents are fundamentally different at the protein level; their engineered polymerases contain unique amino acid modifications that confer dramatic improvements to the function of the enzyme.
 
Their protein engineering capabilities are the result of a high-throughput
molecular evolution technology. This platform is being used to develop a portfolio of designer polymerases engineered specifically for applications such as qPCR, Fast PCR, high fidelity PCR, crude sample PCR, next-generation DNA sequencing, and molecular diagnostics.
 
For more information on the recommended applications and features of the engineered products please download the
Enzyme Selection Guide.
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KAPA SYBR FAST qPCR Kits
 
KAPA SYBR® FAST qPCR Kits are designed for the highest performance in real-time PCR. The kit is based on a novel DNA polymerase engineered through a process of molecular evolution. The result is a unique enzyme, specifically evolved for qPCR using SYBR® Green I dye chemistry.
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KAPA2G Robust HotStart
 
KAPA2G Robust HotStart is a highly robust and versatile second-generation enzyme derived through a process of molecular evolution. The novel amino acid mutations in the flagship KAPA2G Robust DNA Polymerase offer higher processivity and specific activity, which translates to robust performance.
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KAPA Blood PCR Kits
 
Eliminate the need for DNA purification with the first polymerase engineered for PCR direct from blood. KAPA Blood PCR Kits are available in two optimized, easy-to-use 2x formats containing all PCR components except primers and template (whole blood).
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KAPA2G Fast HotStart
 
KAPA2G Fast HotStart is a second-generation enzyme derived through a process of molecular evolution. KAPA2G Fast DNA Polymerase was specifically engineered for higher processivity and speed, offering significantly faster extension rates than wild-type Taq polymerase.
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KAPAHiFi HotStart DNA Polymerase
 
A second-generation polymerase engineered for extreme fidelity and robustness. KAPAHiFi HotStart DNA Polymerase is a novel, single-enzyme system that exhibits industry-leading performance when compared with other high fidelity polymerases and polymerase blends.
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KAPA2G Robust DNA Polymerase
 
A second generation DNA polymerase engineered for extreme robustness and difficult templates. KAPA2G Robust DNA Polymerase is a highly versatile engineered enzyme that was derived from Kapa Biosystems’ molecular evolution platform.
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KAPAHiFi DNA Polymerase
 
A second-generation polymerase engineered for extreme fidelity and robustness. KAPAHiFi DNA Polymerase is a novel, single-enzyme system that exhibits industry-leading performance when compared with other high fidelity polymerases and polymerase blends.
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KAPA2G Fast DNA Polymerase
 
A second generation DNA polymerase engineered for extreme speed - also available in hot start for superior specificity and high-throughput PCR. Designed specifically for speed and high performance.
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KAPA PROBE FAST qPCR Kits
 
KAPA PROBE FAST qPCR Kits contain a ready-to-use master mix for highly sensitive and accurate real-time PCR using sequence-specific fluorogenic probe chemistries including hydrolysis probes (e.g. TaqMan®), FRET probes, and displacement probes (e.g. molecular beacons).
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Application Notes
 
Application Notes
Kapa Logo.gif
Customer Testimonials
 
Customer Testimonials
 
Kapa Biosystems
Kapa Biosystems

Despite the various claims of other reagents suppliers, all commercially available Taq polymerase is the same wild-type enzyme-any differences in performance are due to buffer formulation and/or enzyme concentration.
 
There are only a limited number of DNA polymerases that have been modified to improve their performance for laboratory applications. Kapa Biosystems' next-gen PCR reagents are fundamentally different at the protein level; their engineered polymerases contain unique amino acid modifications that confer dramatic improvements to the function of the enzyme.
 
Their protein engineering capabilities are the result of a high-throughput
molecular evolution technology. This platform is being used to develop a portfolio of designer polymerases engineered specifically for applications such as qPCR, Fast PCR, high fidelity PCR, crude sample PCR, next-generation DNA sequencing, and molecular diagnostics.
 
For more information on the recommended applications and features of the engineered products please download the
Enzyme Selection Guide.